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1

Shaping humoral immunity to vaccines through antigen-displaying nanoparticles

Irvine, Darrell J, Read, Benjamin J

Journal:

Current Opinion in Immunology

Year:

2020

Language:

english

File:

PDF, 573 KB

english, 2020

2

Synthetic Nanoparticles for Vaccines and Immunotherapy

Irvine, Darrell J., Hanson, Melissa C., Rakhra, Kavya, Tokatlian, Talar

Journal:

Chemical Reviews

Year:

2015

Language:

english

File:

PDF, 18.05 MB

english, 2015

3

Nanoparticle anchoring targets immune agonists to tumors enabling anti-cancer immunity without systemic toxicity

Zhang, Yuan, Li, Na, Suh, Heikyung, Irvine, Darrell J.

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 4.46 MB

english, 2018

4

Drug Delivery: Nano-Layered Microneedles for Transcutaneous Delivery of Polymer Nanoparticles and Plasmid DNA (Adv. Mater. 43/2010)

Peter C. DeMuth, Xingfang Su, Raymond E. Samuel, Paula T. Hammond, Darrell J. Irvine

Journal:

Advanced Materials

Year:

2010

File:

PDF, 4.93 MB

2010

5

Surface-structure-regulated cell-membrane penetration by monolayer-protected nanoparticles

Verma, Ayush, Uzun, Oktay, Hu, Yuhua, Hu, Ying, Han, Hee-Sun, Watson, Nicki, Chen, Suelin, Irvine, Darrell J., Stellacci, Francesco

Journal:

Nature Materials

Year:

2008

Language:

english

File:

PDF, 1.57 MB

english, 2008

6

In Vitro and in Vivo mRNA Delivery Using Lipid-Enveloped pH-Responsive Polymer Nanoparticles

Su, Xingfang, Fricke, Jennifer, Kavanagh, Daniel G., Irvine, Darrell J.

Journal:

Molecular Pharmaceutics

Year:

2011

Language:

english

File:

PDF, 4.91 MB

english, 2011

7

Engineering Nano- and Microparticles to Tune Immunity

James J. Moon, Bonnie Huang, Darrell J. Irvine

Journal:

Advanced Materials

Year:

2012

Language:

english

File:

PDF, 9.29 MB

english, 2012

8

Effect of Particle Diameter and Surface Composition on the Spontaneous Fusion of Monolayer-Protected Gold Nanoparticles with Lipid Bilayers

Van Lehn, Reid C., Atukorale, Prabhani U., Carney, Randy P., Yang, Yu-Sang, Stellacci, Francesco, Irvine, Darrell J., Alexander-Katz, Alfredo

Journal:

Year:

2013

Language:

english

File:

PDF, 8.06 MB

english, 2013

9

SPIE Proceedings [SPIE SPIE Defense, Security, and Sensing - Baltimore, Maryland, USA (Monday 29 April 2013)] Airborne Intelligence, Surveillance, Reconnaissance (ISR) Systems and Applications X - Real-time video image quality estimation supports enhanced tracker performance

Irvine, John M., Wood, Richard J., Henry, Daniel J., Lange, Davis A., Linne von Berg, Dale, Rajan, S. Danny, Walls, Thomas J., Young, Darrell L.

Year:

2013

Language:

english

File:

PDF, 995 KB

english, 2013

10

D YNAMICS OF C ELL S URFACE M OLECULES D URING T C ELL R ECOGNITION

Davis, Mark M., Krogsgaard, Michelle, Huppa, Johannes B., Sumen, Cenk, Purbhoo, Marco A., Irvine, Darrell J., Wu, Lawren C., Ehrlich, Lauren

Journal:

Annual Review of Biochemistry

Year:

2003

Language:

english

File:

PDF, 767 KB

english, 2003

11

Cytosolic Delivery Mediated via Electrostatic Surface Binding of Protein, Virus, or siRNA Cargos to pH-Responsive Core−Shell Gel Particles

Hu, Yuhua, Atukorale, Prabhani U., Lu, James J., Moon, James J., Um, Soong Ho, Cho, Eun Chol, Wang, Yana, Chen, Jianzhu, Irvine, Darrell J.

Journal:

Biomacromolecules

Year:

2009

Language:

english

File:

PDF, 2.77 MB

english, 2009

12

Computer Simulations of Self-Assembling Comb Copolymers

Irvine, Darrel J., Gersappe, Dilip, Balazs, Anna C.

Journal:

Year:

1995

Language:

english

File:

PDF, 2.02 MB

english, 1995

13

Manipulating the Selection Forces during Affinity Maturation to Generate Cross-Reactive HIV Antibodies

Wang, Shenshen, Mata-Fink, Jordi, Kriegsman, Barry, Hanson, Melissa, Irvine, Darrell J., Eisen, Herman N., Burton, Dennis R., Wittrup, K. Dane, Kardar, Mehran, Chakraborty, Arup K.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.61 MB

english, 2015

14

SPIE Proceedings [SPIE SPIE Defense + Security - Baltimore, Maryland, United States (Monday 20 April 2015)] Airborne Intelligence, Surveillance, Reconnaissance (ISR) Systems and Applications XII - Context and quality estimation in video for enhanced event detection

Henry, Daniel J., Gosian, Gregory J., Lange, Davis A., Linne von Berg, Dale, Walls, Thomas J., Young, Darrell L., Irvine, John M., Wood, Richard J.

Year:

2015

Language:

english

File:

PDF, 3.09 MB

english, 2015

15

A Receptor for All Occasions

Irvine, Darrell J.

Journal:

Year:

2016

Language:

english

File:

PDF, 261 KB

english, 2016

16

Structurally Programmed Assembly of Translation Initiation Nanoplex for Superior mRNA Delivery

Li, Jiahe, Wang, Wade, He, Yanpu, Li, Yingzhong, Yan, Emily Z., Zhang, Ketian, Irvine, Darrell J., Hammond, Paula T.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.92 MB

english, 2017

17

Enhancing T cell therapy through TCR-signaling-responsive nanoparticle drug delivery

Tang, Li, Zheng, Yiran, Melo, Mariane Bandeira, Mabardi, Llian, Castaño, Ana P, Xie, Yu-Qing, Li, Na, Kudchodkar, Sagar B, Wong, Hing C, Jeng, Emily K, Maus, Marcela V, Irvine, Darrell J

Journal:

Nature Biotechnology

Year:

2018

Language:

english

File:

PDF, 2.61 MB

english, 2018

18

Synthetic Charge-Invertible Polymer for Rapid and Complete Implantation of Layer-by-Layer Microneedle Drug Films for Enhanced Transdermal Vaccination

He, Yanpu, Hong, Celestine, Li, Jiahe, Howard, MayLin T., Li, Yingzhong, Turvey, Michelle E., Uppu, Divakara S. S. M., Martin, John R., Zhang, Ketian, Irvine, Darrell J., Hammond, Paula T.

Journal:

Year:

2018

Language:

english

File:

PDF, 1.41 MB

english, 2018

19

STEPS to Care: Translating an Evidence-Informed HIV Care Coordination Program Into a Field-Tested Online Practice Improvement Toolkit

O'Donnell, Lydia, Irvine, Mary K., Wilkes, Aisha L., Rwan, Julie, Myint-U, Athi, Leow, Deborah McLean, Whittier, David, Harriman, Graham, Bessler, Patricia, Higa, Darrel, Courtenay-Quirk, Cari

Journal:

AIDS Education & Prevention

Year:

2020

File:

PDF, 445 KB

2020

20

Nano-Layered Microneedles for Transcutaneous Delivery of Polymer Nanoparticles and Plasmid DNA

Peter C. DeMuth, Xingfang Su, Raymond E. Samuel, Paula T. Hammond, Darrell J. Irvine

Journal:

Advanced Materials

Year:

2010

Language:

english

File:

PDF, 839 KB

english, 2010

21

Membrane Anchored Immunostimulatory Oligonucleotides for In Vivo Cell Modification and Localized Immunotherapy

Dr. Haipeng Liu, Brandon Kwong, Prof. Darrell J. Irvine

Journal:

Angewandte Chemie

Year:

2011

Language:

english

File:

PDF, 595 KB

english, 2011

22

Oligonucleotide Delivery by Cell-Penetrating “Striped” Nanoparticles

Dr. Christopher M. Jewell, Dr. Jin-Mi Jung, Prabhani U. Atukorale, Randy P. Carney, Prof. Francesco Stellacci, Prof. Darrell J. Irvine

Journal:

Angewandte Chemie

Year:

2011

Language:

english

File:

PDF, 1.15 MB

english, 2011

23

Membrane Anchored Immunostimulatory Oligonucleotides for In Vivo Cell Modification and Localized Immunotherapy

Dr. Haipeng Liu, Brandon Kwong, Prof. Darrell J. Irvine

Journal:

Angewandte Chemie International Edition

Year:

2011

Language:

english

File:

PDF, 585 KB

english, 2011

24

Oligonucleotide Delivery by Cell-Penetrating “Striped” Nanoparticles

Dr. Christopher M. Jewell, Dr. Jin-Mi Jung, Prabhani U. Atukorale, Randy P. Carney, Prof. Francesco Stellacci, Prof. Darrell J. Irvine

Journal:

Angewandte Chemie International Edition

Year:

2011

Language:

english

File:

PDF, 1.14 MB

english, 2011

25

Inverse opal hydrogel-collagen composite scaffolds as a supportive microenvironment for immune cell migration

Agnieszka N. Stachowiak, Darrell J. Irvine

Journal:

Journal of Biomedical Materials Research Part A

Year:

2008

Language:

english

File:

PDF, 554 KB

english, 2008

26

Engulfing tumors with synthetic extracellular matrices for cancer immunotherapy

Yuki Hori, Patrick J. Stern, Richard O. Hynes, Darrell J. Irvine

Journal:

Year:

2009

Language:

english

File:

PDF, 1.58 MB

english, 2009

27

Engineering chemoattractant gradients using chemokine-releasing polysaccharide microspheres

Yana Wang, Darrell J. Irvine

Journal:

Year:

2011

Language:

english

File:

PDF, 1001 KB

english, 2011

28

Enhancing cell therapies from the outside in: Cell surface engineering using synthetic nanomaterials

Matthias T. Stephan, Darrell J. Irvine

Journal:

Year:

2011

Language:

english

File:

PDF, 809 KB

english, 2011

29

Directed cell migration via chemoattractants released from degradable microspheres

Xiaojun Zhao, Siddhartha Jain, H. Benjamin Larman, Sandra Gonzalez, Darrell John Irvine

Journal:

Year:

2005

Language:

english

File:

PDF, 676 KB

english, 2005

30

Modular injectable matrices based on alginate solution/microsphere mixtures that gel in situ and co-deliver immunomodulatory factors

Yuki Hori, Amy M. Winans, Darrell J. Irvine

Journal:

Acta Biomaterialia

Year:

2009

Language:

english

File:

PDF, 1023 KB

english, 2009

31

Injectable dendritic cell-carrying alginate gels for immunization and immunotherapy

Yuki Hori, Amy M. Winans, Catherine C. Huang, Elizabeth M. Horrigan, Darrell J. Irvine

Journal:

Year:

2008

Language:

english

File:

PDF, 1.71 MB

english, 2008

32

Induction of potent anti-tumor responses while eliminating systemic side effects via liposome-anchored combinatorial immunotherapy

Brandon Kwong, Haipeng Liu, Darrell J. Irvine

Journal:

Year:

2011

Language:

english

File:

PDF, 1.80 MB

english, 2011

33

Patterned surfaces as tools to study ligand recognition and synapse formation by T cells

Darrell J Irvine, Junsang Doh, Bonnie Huang

Journal:

Current Opinion in Immunology

Year:

2007

Language:

english

File:

PDF, 1.14 MB

english, 2007

34

Interleukin-7 Receptor Signaling Network: An Integrated Systems Perspective

Palmer, Megan J, Mahajan, Vinay S, Trajman, Lily C, Irvine, Darrell J, Lauffenburger, Douglas A, Chen, Jianzhu

Journal:

Cellular & Molecular Immunology

Year:

2008

Language:

english

File:

PDF, 4.07 MB

english, 2008

35

Direct observation of ligand recognition by T cells

Irvine, Darrell J., Purbhoo, Marco A., Krogsgaard, Michelle, Davis, Mark M.

Journal:

Year:

2002

Language:

english

File:

PDF, 541 KB

english, 2002

36

A role for the immunological synapse in lineage commitment of CD4 lymphocytes

Maldonado, Roberto A., Irvine, Darrell J., Schreiber, Robert, Glimcher, Laurie H.

Journal:

Year:

2004

Language:

english

File:

PDF, 437 KB

english, 2004

37

Regulation of thymocyte positive selection and motility by GIT2

Phee, Hyewon, Dzhagalov, Ivan, Mollenauer, Marianne, Wang, Yana, Irvine, Darrell J, Robey, Ellen, Weiss, Arthur

Journal:

Nature Immunology

Year:

2010

Language:

english

File:

PDF, 1.08 MB

english, 2010

38

Corrigendum: T cell killing does not require the formation of a stable mature immunological synapse

Purbhoo, Marco A, Irvine, Darrell J, Huppa, Johannes B, Davis, Mark M

Journal:

Nature Immunology

Year:

2004

Language:

english

File:

PDF, 52 KB

english, 2004

39

T cell killing does not require the formation of a stable mature immunological synapse

Purbhoo, Marco A, Irvine, Darrell J, Huppa, Johannes B, Davis, Mark M

Journal:

Nature Immunology

Year:

2004

Language:

english

File:

PDF, 553 KB

english, 2004

40

CD4 enhances T cell sensitivity to antigen by coordinating Lck accumulation at the immunological synapse

Li, Qi-Jing, Dinner, Aaron R, Qi, Shuyan, Irvine, Darrell J, Huppa, Johannes B, Davis, Mark M, Chakraborty, Arup K

Journal:

Nature Immunology

Year:

2004

Language:

english

File:

PDF, 590 KB

english, 2004

41

Therapeutic cell engineering with surface-conjugated synthetic nanoparticles

Stephan, Matthias T, Moon, James J, Um, Soong Ho, Bershteyn, Anna, Irvine, Darrell J

Journal:

Nature Medicine

Year:

2010

Language:

english

File:

PDF, 1.52 MB

english, 2010

42

Drug delivery: One nanoparticle, one kill

Irvine, Darrell J.

Journal:

Nature Materials

Year:

2011

Language:

english

File:

PDF, 429 KB

english, 2011

43

Bio-inspired, bioengineered and biomimetic drug delivery carriers

Yoo, Jin-Wook, Irvine, Darrell J., Discher, Dennis E., Mitragotri, Samir

Journal:

Nature Reviews Drug Discovery

Year:

2011

Language:

english

File:

PDF, 1.43 MB

english, 2011

44

Synapse-directed delivery of immunomodulators using T-cell-conjugated nanoparticles

Matthias T. Stephan, Sirkka B. Stephan, Peter Bak, Jianzhu Chen, Darrell J. Irvine

Journal:

Year:

2012

Language:

english

File:

PDF, 1.77 MB

english, 2012

45

Synthetic mRNA-loaded Nanoparticles Elicit Mucosal IL-17+ and IFNγ+ T Cells

Jennifer Fricke, Edward Seung, Valerie Vassor, Andrew Martin Tager, Rajesh Tim Gandhi, Bruce Walker, Darrell Irvine, Daniel Kavanagh

Journal:

Clinical Immunology

Year:

2010

Language:

english

File:

PDF, 43 KB

english, 2010

46

Particulate vaccines: on the quest for optimal delivery and immune response

Marie-Luce De Temmerman, Joanna Rejman, Jo Demeester, Darrell J. Irvine, Bruno Gander, Stefaan C. De Smedt

Journal:

Drug Discovery Today

Year:

2011

Language:

english

File:

PDF, 590 KB

english, 2011

47

Robust IgG responses to nanograms of antigen using a biomimetic lipid-coated particle vaccine

Anna Bershteyn, Melissa C. Hanson, Monica P. Crespo, James J. Moon, Adrienne V. Li, Heikyung Suh, Darrell J. Irvine

Journal:

Journal of Controlled Release

Year:

2012

Language:

english

File:

PDF, 1.12 MB

english, 2012

48

A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples

Margaret E. Ackerman, Brian Moldt, Richard T. Wyatt, Anne-Sophie Dugast, Elizabeth McAndrew, Stephen Tsoukas, Stephanie Jost, Christoph T. Berger, Gaia Sciaranghella, Qingquan Liu, Darrell J. Irvine,

Journal:

Journal of Immunological Methods

Year:

2011

Language:

english

File:

PDF, 1.37 MB

english, 2011

49

Corrigendum to “A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples”

Margaret E. Ackerman, Brian Moldt, Richard T. Wyatt, Anne-Sophie Dugast, Elizabeth McAndrew, Stephen Tsoukas, Stephanie Jost, Christoph T. Berger, Gaia Sciaranghella, Qingquan Liu, Darrell J. Irvine,

Journal:

Journal of Immunological Methods

Year:

2012

Language:

english

File:

PDF, 121 KB

english, 2012

50

Block Copolymer Micelles as Nanocontainers for Controlled Release of Proteins from Biocompatible Oil Phases

Miller, Andrew C., Bershteyn, Anna, Tan, Wuisiew, Hammond, Paula T., Cohen, Robert E., Irvine, Darrell J.

Journal:

Biomacromolecules

Year:

2009

Language:

english

File:

PDF, 1.74 MB

english, 2009

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